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Conolidine’s analgesic outcomes stem from its conversation with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors within the central anxious method, conolidine modulates alternate molecular targets. A Science Advancements analyze observed that conolidine interacts Along with the atypical chemokine receptor ACKR3/CXCR7, w

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